According to God of Prompt on Twitter, Andrej Karpathy's viral AI coding rant was transformed into a system prompt designed to optimize agentic coding workflows, especially for Claude. The prompt focuses on reducing common LLM coding mistakes such as unchecked assumptions, overcomplicated code, and lack of clarification, by enforcing a structured, senior-engineer mindset. As reported by Karpathy, this approach has led to a dramatic shift in software engineering, with engineers now predominantly coding through agentic LLMs like Claude and Codex, moving from manual coding to high-level orchestration. The underlying business opportunity lies in leveraging these new AI-driven workflows to accelerate development, enhance code reliability, and increase productivity, while also preparing organizations for a rapid industry-wide transformation in 2026.